A college student navigates life and school while dealing with a unique predicament — he's living with a beautiful former K-pop idol.

Boo Yong Joo was once a famous surgeon at the peak of his career at a major hospital. But he suddenly gives it all up one day to live in seclusion and work as a neighborhood doctor in a small town. He now goes by “Teacher Kim” and refers to himself as the “Romantic Doctor.” Meanwhile, Kang Dong Joo became a doctor to make something of himself after growing up poor, and he seeks out VIP patients to achieve the success that he desperately wants. Yoon Seo Jung is a passionate young surgeon who is haunted by a mistake from her past and tries to get over it. When Dong Joo and Seo Jung meet the quirky Teacher Kim, their lives and careers will never be the same again.

Gong Woo-Jin is a 30-year-old single man and he works as a set designer. Due to a trauma he experienced 13 years ago, he does not want to have a relationship with others. When Woo Seo-Ri was 17, she fell into a coma. 13 years later, she wakes up from her coma. Her mental age is still that of a 17-year-old, but she is now 30-years-old. Gong Woo-Jin and Woo Seo-Ri get involved with each other and fall in love.

Set during the turbulent time of the fall of Goryeo and the founding of Joseon, two former friends face-off against one another over a woman and the future shape of the nation.

Hyun-Soo is an aspiring drama series writer. She uses "Jane" as her username and begins chatting with username “Chakhan Seupeu” (‘Good Soup’) online. “Chakhan Seupeu” is actually Jung-Sun. He dreams of becoming a French food chef. They meet in real life.

A reinterpretation of Saimdang from the Joseon times. She was a genius artist and passionate lover. Lee Young-ae takes on two roles; a college professor who specializes in Korea Art History and Saimdang.