Can the logical brain mix with volatile emotions? Han Seung Joo is a star neurosurgeon who is renowned for his extraordinary memory. To him, the world is very clear-cut and logical. But his strong personality frequently places him at odds with his fellow neurosurgeon, Cha Jae Hwan, who is the son of the hospital director. When they both fall for Joo In Ah, an endocrinologist who is obsessed with hormones, they take competition to a whole new level.

The Slave Hunters is a 2010 South Korean action historical drama set in the Joseon Dynasty about a slave hunter who is tracking down a general-turned-runaway slave as well as searching for the woman he loves. It aired on KBS2 from January 6 to March 25, 2010 on Wednesdays and Thursdays at 21:55 for 24 episodes. An adequate display of muscular brawn, intricate yet gritty fight scenes, bawdy humor and eloquent moments of pathos and humanity made the series both visually and intellectually appealing to audiences. Critics gave special mention to director Kwak Jung-hwan's lush cinematography, the use of a Red One camera giving each shot its theater-worthy luster. The hit series topped the ratings chart for 7 consecutive weeks, averaging 31.7% and reaching a peak of 35.9%. The series was honored at the Seoul International Drama Awards, and the KBS Drama Awards. Jang also received a best actor nomination from the 2011 International Emmy Awards for his performance.