Bizarre clues and a new T-Virus strain lead Agent Chris Redfield and a team of familiar faces to Alcatraz Island to confront a mysterious threat.

A recently adopted child has gone missing and it's up to her parents to find her.

After a series of calamities in Washington D.C., two estranged brothers re-unite and decide to investigate the cause of the nature's unexpected attacks. Will they be able to unravel the mystery?